High pressure homogenizer for sale — lab ($4,500-$8,500), pilot ($25,000-$55,000), industrial ($60,000-$110,000). 2000 bar, CE certified, factory direct, global shipping.
# Smallnm High Pressure Homogenizers ? Lab, Pilot & Industrial
Smallnm is a leading manufacturer of high pressure homogenizers, serving pharmaceutical, biotechnology, food & beverage, cosmetic, and chemical industries worldwide. We offer three product lines covering every scale ? from 10 mL R&D samples to 5000 L/h industrial production.
> You know you need a high pressure homogenizer ? but with lab, pilot, and industrial models ranging from $4,500 to $110,000+, it’s not always clear which one fits your application and budget. This product page gives you everything you need to compare models side by side and request a quote with confidence.
Quick Overview:
Select your profile below to see the right models, specs, and pricing for your needs.
You’re developing a new formulation, running experiments, or producing small batches. You need precision, reproducibility, and the ability to test multiple parameters.
| Recommended Model | Flow Rate | Max Pressure | Min Sample | Price Range |
|---|---|---|---|---|
| —————– | ———– | ————- | ———– | ———— |
| **PTH-10 Lab Homogenizer** | 10?20 L/h | 2000 bar | 25 mL | $4,500?$8,500 |
| **PTH-20 Lab Homogenizer** | 30?50 L/h | 2000 bar | 100 mL | $8,000?$15,000 |
Best for: Liposome R&D, nanoemulsion screening, cell disruption optimization, cosmetic formulation, nanoparticle synthesis ? all with direct scale-up to production.
? View PTH-10 Specs & Configurations ? ? View PTH-20 Specs
> Not sure which lab model? Tell us your application and batch size ? we’ll recommend the exact configuration within 4 hours.
>
> ? Get a Lab-Scale Recommendation ?
You need clinical trial material, pilot batches, or small-scale manufacturing. You need a machine that matches your R&D parameters and can run reliably for production campaigns.
| Recommended Model | Flow Rate | Max Pressure | Automation | Price Range |
|---|---|---|---|---|
| —————– | ———– | ————- | ———– | ———— |
| **500 L/h Pilot Homogenizer** | 100?500 L/h | 2000 bar | Manual to PLC | $25,000?$55,000 |
Best for: Clinical batch liposomes/LNPs, vaccine adjuvant production, plant-based milk pilot runs, production-scale nanoemulsions, small-batch cell disruption.
> Scaling up from lab to pilot? Same pressure and pass parameters ? we’ll help you configure the right valve, automation, and certification package.
>
You’re running a production line and need reliable, continuous operation with high throughput. Uptime, automation, and total cost of ownership are your top priorities.
| Recommended Model | Flow Rate | Max Pressure | Automation | Price Range |
|---|---|---|---|---|
| —————– | ———– | ————- | ———– | ———— |
| **1000 L/h Industrial Homogenizer** | 500?1200 L/h | 2000 bar | PLC / SCADA ready | $60,000?$110,000 |
Available certifications: CE (standard), UL, ATEX, 3-A Sanitary, GMP documentation
Custom options: Hastelloy materials, two-stage valve, integrated heat exchanger, remote monitoring
> Need higher throughput or custom specs? We build custom configurations up to 5000 L/h with your choice of materials, automation, and certs.
>
| Specification | PTH-10 (Lab) | PTH-20 (Lab) | 500 L/h (Pilot) | 1000 L/h (Industrial) |
|---|---|---|---|---|
| ————- | :———–: | :———–: | :————–: | :——————–: |
| **Flow rate** | 10?20 L/h | 30?50 L/h | 100?500 L/h | 500?1200 L/h |
| **Max pressure** | 2000 bar | 2000 bar | 2000 bar | 2000 bar |
| **Min sample** | 25 mL | 100 mL | 25 L | 50 L |
| **Motor power** | 2.2 kW | 4 kW | 15?22 kW | 30?55 kW |
| **Price range** | $4,500?$8,500 | $8,000?$15,000 | $25,000?$55,000 | $60,000?$110,000 |
| **Best for** | R&D, screening | Pre-clinical | Pilot, clinical | Production |
| Industry | Application | Recommended Scale | Target Size |
|---|---|---|---|
| ——— | ———— | —————– | ————- |
| **Pharma / Biotech** | [Liposome Manufacturing](/liposome-preparation-homogenizer/) | Lab ? Pilot | 50?500 nm |
| **Pharma / Biotech** | [Lipid Nanoparticle (LNP)](/lipid-nanoparticle-homogenizer/) | Lab ? Pilot | 50?150 nm |
| **Pharma / Biotech** | [Cell Disruption](/cell-disruption-homogenizer/) | Pilot ? Industrial | Cell fragments |
| **Pharma / Biotech** | [Nanosuspensions](/nanosuspension-homogenizer/) | Lab ? Pilot | 100?500 nm |
| **Pharma / Biotech** | [Vaccine Adjuvants](/vaccine-adjuvant-homogenizer/) | Pilot | < 200 nm |
| **Food & Beverage** | [Dairy Homogenization](/dairy-milk-homogenizer/) | Industrial | < 1 ?m |
| **Food & Beverage** | [Plant-Based Milk](/plant-based-milk-homogenizer/) | Pilot ? Industrial | < 5 ?m |
| **Food & Beverage** | [Nanoemulsions](/nanoemulsion-preparation-homogenizer/) | Any scale | 50?200 nm |
| **Cosmetics** | [Cream, Lotion, Serum](/cosmetic-homogenizer/) | Lab ? Pilot | 100?500 nm |
| **Chemical** | [Dispersions, Battery, Ink](/18-more-industries-homogenizer-guide/) | Industrial | Varies |
| Advantage | Detail |
|---|---|
| ———– | ——– |
| **Factory Direct Pricing** | 20?40% savings vs distributor pricing ? you pay for the machine, not the middleman |
| **Up to 2000 bar** | Handles the most demanding applications from dairy to drug nanocrystals |
| **CE Certified** | Full compliance with EU safety standards; UL, ATEX, 3-A, GMP available |
| **Global Shipping** | Export to 50+ countries with remote + on-site technical support |
| **Scalable by Design** | Same process parameters from PTH-10 to 1000 L/h ? no re-optimization needed |
| **Custom Configurations** | Materials (SS316L, Hastelloy), valves, automation, and certifications |
| **Free Sample Testing** | Send us your material ? we’ll process it and send a full report with recommended model and parameters |
| Option | Available Choices | Lead Time |
|---|---|---|
| ——– | —————— | ———– |
| **Materials** | SS316L (standard), Hastelloy C-276, Duplex SS | +2?4 weeks |
| **Valves** | Flat, knife-edge, two-stage, ceramic, tungsten carbide | +1?2 weeks |
| **Seals** | PTFE, Viton, EPDM, silicone | +1 week |
| **Automation** | Manual, semi-auto, PLC, SCADA | +4?8 weeks |
| **Certifications** | CE (standard), UL, ATEX, 3-A, GMP documentation | Varies |
| **Heat exchanger** | Integrated plate, tube-in-tube, jacket | +2?4 weeks |
> ? Not sure which model fits your application? Tell us your product, target particle size, and required throughput ? we’ll recommend the exact configuration with a firm price within 24 hours.
Please include:
Smallnm provides free product testing ? send us your sample and we will process it on our lab homogenizer with a detailed process report.
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50+ expert answers to high pressure homogenizer questions — working principle, applications, selection, maintenance, costs, troubleshooting. Everything you need in one place.
